http://chemjobber.blogspot.fr/2012/03/whats-job-market-for-chemical.html
Interesting post but don't forget to check actual offers from industry because they do exist!
2012-10-14
Postdoctoral position in chemical biology/optogenetics
Paris, France
École Normale Supérieure, Department of Chemistry
The École normale supérieure (ENS) is an elite higher education institution for advanced
undergraduate and graduate studies, and a prestigious French research center in the heart of
Paris (http://www.ens.fr/).
The group of biophysical chemistry at the department of chemistry is recruiting a postdoctoral
fellow to work on the development of optogenetic tools to spatiotemporally regulate protein
functions in living cells and organisms.
Our group is a multidisciplinary group gathering expertise in chemical biology, biophysics,
synthetic and analytical chemistry with a broad interest in the development of techniques to
image and control biological processes.
The candidate must hold a PhD in molecular biology, chemistry or related fields and have a
strong interest in the development of methods at the chemistry/biology interface. An expertise
in the fields of protein engineering, molecular and cell biology, biophysical chemistry and
microscopy will be a plus. The candidate is expected to be self-driven, to have strong workcapacity
and enthusiasm for science, and to have good communication skills.
This post, supported by an ANR grant awarded to Dr. Arnaud Gautier, is available from
February 2013 and is offered on a fixed term contract of 18 months.
Interested individuals should send a cover letter explaining relevant work experience,
curriculum vitae and contact details of two referees by e-mail to Dr. Arnaud Gautier
(arnaud.gautier@ens.fr)
Webpage Arnaud Gautier : http://www1.chimie.ens.fr/Imsmo/Arnaud_Gautier/Gautier.html
Webpage group of biophysical chemistry : http://www1.chimie.ens.fr/Imsmo/
École Normale Supérieure, Department of Chemistry
The École normale supérieure (ENS) is an elite higher education institution for advanced
undergraduate and graduate studies, and a prestigious French research center in the heart of
Paris (http://www.ens.fr/).
The group of biophysical chemistry at the department of chemistry is recruiting a postdoctoral
fellow to work on the development of optogenetic tools to spatiotemporally regulate protein
functions in living cells and organisms.
Our group is a multidisciplinary group gathering expertise in chemical biology, biophysics,
synthetic and analytical chemistry with a broad interest in the development of techniques to
image and control biological processes.
The candidate must hold a PhD in molecular biology, chemistry or related fields and have a
strong interest in the development of methods at the chemistry/biology interface. An expertise
in the fields of protein engineering, molecular and cell biology, biophysical chemistry and
microscopy will be a plus. The candidate is expected to be self-driven, to have strong workcapacity
and enthusiasm for science, and to have good communication skills.
This post, supported by an ANR grant awarded to Dr. Arnaud Gautier, is available from
February 2013 and is offered on a fixed term contract of 18 months.
Interested individuals should send a cover letter explaining relevant work experience,
curriculum vitae and contact details of two referees by e-mail to Dr. Arnaud Gautier
(arnaud.gautier@ens.fr)
Webpage Arnaud Gautier : http://www1.chimie.ens.fr/Imsmo/Arnaud_Gautier/Gautier.html
Webpage group of biophysical chemistry : http://www1.chimie.ens.fr/Imsmo/
Post Doctoral Fellow - chemical biology
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| Postdoctoral fellowships in chemical biology. The Ellis-Davies lab is well known for work at the interface of chemistry and biology (e.g. photosensitive, or caged, neurotransmitters for the stimulation of nerve cells). Two postdoctoral positions are available in our new labs at Mount Sinai School of Medicine to do make novel chromophores for photochemical uncaging in living animals using modern synthetic organic chemistry. The successful candidates will have the opportunity to interact with biologists, and learn about pharmacology and neuroscience. Our papers appear in high profile journals (eg. Nature Chemical Biology, Nature Methods, Nature Protocols, ChemBioChem, ACS Chemical Neuroscience, etc.). | |||||||||||
| Job Qualifications: | |||||||||||
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Candidates MUST
HAVE a Ph.D. in synthetic organic chemistry for consideration. Please
send these important details: 1. education history; 2. webpages of three
references; and 3. list of publications. To apply for this Post Doctoral Fellow, 867 - Neurosciences, PD12-1445160 position, click on Complete Application . | |||||||||||
PhD Student Synthetic Organic Chemistry & Chemical Biology
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We are looking for
A PhD candidate with a strong background in synthetic organic chemistry and a keen interest in biology to investigate microbial carbohydrate derivatives. Many symbiotic and pathogenic microbes that interact with the human body display a wide range of structurally unique sialic acid carbohydrates. The roles these microbial sialic acids play in the functioning of these microbes are currently not well understood. The initial goal of the project will be to develop a total synthesis for these microbial sialic acids. Next, you will use the developed synthetic routes to design and synthesize modified derivatives with additional functionalities (e.g microbial sialic acid based inhibitors, activity based probes, glycoarrays, fluorescent substrates). In the final stage of the project you will use these compounds to investigate the role(s) of microbial sialic acids in relevant human-associated microbes. For this interdisciplinary part of the project, involving chemical biology and microbiology, you will receive training in both areas and collaborate with microbiologists at Wageningen University.
Requirements
You should have an MSc degree in Chemistry/ Molecular Sciences, or comparable curriculum. A strong background and solid hands-on experience in synthetic organic chemistry is a prerequisite. A strong interest (or preferentially experience) in chemical biology oriented research is also important. Your affinity for the multidisciplinary and collaborative nature of the project and good written and oral communication skills in English are additional requirements.
We offer
We offer you a temporary position for a period of 1.5 years with extension of 2.5 years after successful evaluation. Gross salary per month € 2042 in the first year rising up to € 2612 per month in the fourth year.
We not only offer a competitive salary but also good (study) leave and a pension of the ABP Pension Fund.
Additional informationFor more information about this position, please contact dr. Tom Wennekes, Laboratory of Organic Chemistry, telephone number +31 317481268, e-mail tom.wennekes@wur.nl. For more information about the contractual aspects, please contact Mrs. N. de Vries (HR-advisor), e-mail nicole.devries@wur.nl.
Interested?
The organization
The Laboratory of Organic Chemistry (www.orc.wur.nl) constitutes a large and interdisciplinary research team. We investigate the design, synthesis and behavior of (bio)active organic surfaces & molecules to address questions in the area of life sciences. Recently published examples of our research include biofunctionalized organic monolayers and microchannels, chemo-enzymatic synthesis & glycobiology of ganglioside analogues, immobilized enzymes, and bio-organic nanoparticles (in journals as Angew. Chem., J. Am. Chem. Soc., Chem. Com., ChemBioChem, OBC, Glycobiology, Carbohydrate Res.). Our laboratories are well-equipped with all the facilities & instruments required for the synthesis and evaluation of complex (bio)molecules & organic surfaces, and have an experienced technical staff.
The Agrotechnology & Food Sciences Group
is part of Wageningen UR where fundamental and applied sciences
complement each other. As an important European player, we carry out
top-level research and work alongside authoritative partners within the
international business world as well as the government on “Healthy food
in a biobased society”. We have a crucial role in innovations within the
market. Entrepreneurship and professionalism are what define us. In
short, we are an interesting, international employer of stature.
Wageningen University and Research CentreDelivering a substantial contribution to the quality of life. That's our focus – each and every day. Within our domain, healthy food and living environment, we search for answers to issues affecting society – such as sustainable food production, climate change and alternative energy. Of course, we don’t do this alone. Every day, 6,500 people work on ‘the quality of life’, turning ideas into reality, on a global scale. Could you be one of these people? We give you the space you need. For further information about working at Wageningen UR, take a look at www.jobsat.wur.nl. Acquisition regarding this vacancy is not appreciated. | |||||||||||||
 Click here to apply for this job | |||||||||||||
Senior Scientist, Chemical Biology - Pfizer
Senior Scientist, Chemical Biology - La Jolla, California
Org Marketing Statement
Pfizer Inc: Working together for a healthier world
Founded in 1849, Pfizer is the world's premier biopharmaceutical company taking new approaches to better health. We discover, develop, manufacture and deliver quality, safe and effective prescription medicines to treat and help prevent disease for both people and animals. We also partner with healthcare providers, governments and local communities around the world to expand access to our medicines and to provide better quality health care and health system support. At Pfizer, colleagues in more than 90 countries work every day to help people stay happier and healthier longer and to reduce the human and economic burden of disease worldwide.
Responsibilities
Position Purpose:
Develop and implement chemical biology techniques to advance projects across the Oncology portfolio, primarily through the design and application of chemical probes in complex biological systems.
Primary Duties:
- Design and carry out experiments with functional chemical probes to address specific project needs across the Oncology Research Unit (ORU).
- Work in collaboration with ORU biology to design and execute experiments aimed at answering key biological questions.
- Work in collaboration with the Worldwide Medicinal Chemistry Design and Synthesis groups to conceive and prepare chemical probes.
- Apply and/or develop affinity/activity-based proteomic probes to profile the functional state of enzyme targets in native biological systems and assess selectivity and/or safety of compounds.
- Design of photoaffinity probes and conduct photoaffinity labeling experiments for covalent capture of targets.
- Build effective partnerships with the biophysics group in the ORU and the MS proteomics group in Worldwide Medicinal Chemistry.
- Expand the global chemical proteomics toolbox. Where applicable, use click chemistries to build functional molecules in situ.
- Use chemical proteomics to elucidate biological targets of active molecules from phenotypic screens to expedite drug discovery.
- Design and application of fluorescent probes for live cell imaging studies.
Qualifications
Educational Qualifications:
Doctoral level degree or equivalent experience in chemical biology or related area
Training and Experience:
- Strong track record of delivering biological insights through chemical biology experimentation.
- Highly skilled synthetic chemist with comprehensive knowledge of building chemical biology probes.
- Highly skilled laboratory experimentalist with experience of working on biological systems (cells/cell lysates/ex vivo tissues etc).
- Experience with standard methods used in chemical biology including: protein purification/enrichment, chromatography (size exclusion, ion exchange, affinity) immunoprecipitation, gel electrophoresis; Western blotting.
Preferred:
- Post doctorate in chemical biology or related area.
- Target identification and mechanism of action elucidation experience.
- Comfortable interpreting MS data for identification of target proteins.
- Experience working in the following areas would be desirable: Click chemistry; photoaffinity cross-linking; in-gel fluorescence; chemical modification of proteins; protein engineering; mammalian tissue culture, SILAC methodology; siRNA for target validation.
Equal Employment Opportunity
Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as employment eligibility verification requirements of the Immigration and Nationality Act. All applicants must have authorization to work for Pfizer in the U.S. In certain circumstances it may be advantageous to Pfizer to support the application(s) for temporary visa classification and/or sponsor applications for permanent residence so that a foreign national colleague can accept or remain in a work assignment in the U. S. For certain classes of temporary visas, the resulting work authorization may be specific to Pfizer and the specific job and/or work site. Pfizer may at its business discretion decide to or refrain from obtaining, maintaining and/or extending the temporary visa status and/or sponsoring a colleague for permanent residency and /or employment eligibility, considering factors such as availability of qualified U.S. workers and the colleague's long-term prospects for securing lawful permanent residence, among other reasons. Employment applicants requiring immigration sponsorship must disclose, when initial application for employment is made, whether or not they are legally authorized to work for Pfizer in the U.S. and, if so, whether that authorization permits them to work in the job they seek. In no case should Pfizer's support of a colleague's temporary visa application or sponsorship of a colleague for permanent residence be construed to guarantee success of that application or amend or otherwise invalidate the "at-will" employment relationship between the colleague and Pfizer.
Pfizer Inc: Working together for a healthier world
Founded in 1849, Pfizer is the world's premier biopharmaceutical company taking new approaches to better health. We discover, develop, manufacture and deliver quality, safe and effective prescription medicines to treat and help prevent disease for both people and animals. We also partner with healthcare providers, governments and local communities around the world to expand access to our medicines and to provide better quality health care and health system support. At Pfizer, colleagues in more than 90 countries work every day to help people stay happier and healthier longer and to reduce the human and economic burden of disease worldwide.
Responsibilities
Position Purpose:
Develop and implement chemical biology techniques to advance projects across the Oncology portfolio, primarily through the design and application of chemical probes in complex biological systems.
Primary Duties:
- Design and carry out experiments with functional chemical probes to address specific project needs across the Oncology Research Unit (ORU).
- Work in collaboration with ORU biology to design and execute experiments aimed at answering key biological questions.
- Work in collaboration with the Worldwide Medicinal Chemistry Design and Synthesis groups to conceive and prepare chemical probes.
- Apply and/or develop affinity/activity-based proteomic probes to profile the functional state of enzyme targets in native biological systems and assess selectivity and/or safety of compounds.
- Design of photoaffinity probes and conduct photoaffinity labeling experiments for covalent capture of targets.
- Build effective partnerships with the biophysics group in the ORU and the MS proteomics group in Worldwide Medicinal Chemistry.
- Expand the global chemical proteomics toolbox. Where applicable, use click chemistries to build functional molecules in situ.
- Use chemical proteomics to elucidate biological targets of active molecules from phenotypic screens to expedite drug discovery.
- Design and application of fluorescent probes for live cell imaging studies.
Qualifications
Educational Qualifications:
Doctoral level degree or equivalent experience in chemical biology or related area
Training and Experience:
- Strong track record of delivering biological insights through chemical biology experimentation.
- Highly skilled synthetic chemist with comprehensive knowledge of building chemical biology probes.
- Highly skilled laboratory experimentalist with experience of working on biological systems (cells/cell lysates/ex vivo tissues etc).
- Experience with standard methods used in chemical biology including: protein purification/enrichment, chromatography (size exclusion, ion exchange, affinity) immunoprecipitation, gel electrophoresis; Western blotting.
Preferred:
- Post doctorate in chemical biology or related area.
- Target identification and mechanism of action elucidation experience.
- Comfortable interpreting MS data for identification of target proteins.
- Experience working in the following areas would be desirable: Click chemistry; photoaffinity cross-linking; in-gel fluorescence; chemical modification of proteins; protein engineering; mammalian tissue culture, SILAC methodology; siRNA for target validation.
Equal Employment Opportunity
Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as employment eligibility verification requirements of the Immigration and Nationality Act. All applicants must have authorization to work for Pfizer in the U.S. In certain circumstances it may be advantageous to Pfizer to support the application(s) for temporary visa classification and/or sponsor applications for permanent residence so that a foreign national colleague can accept or remain in a work assignment in the U. S. For certain classes of temporary visas, the resulting work authorization may be specific to Pfizer and the specific job and/or work site. Pfizer may at its business discretion decide to or refrain from obtaining, maintaining and/or extending the temporary visa status and/or sponsoring a colleague for permanent residency and /or employment eligibility, considering factors such as availability of qualified U.S. workers and the colleague's long-term prospects for securing lawful permanent residence, among other reasons. Employment applicants requiring immigration sponsorship must disclose, when initial application for employment is made, whether or not they are legally authorized to work for Pfizer in the U.S. and, if so, whether that authorization permits them to work in the job they seek. In no case should Pfizer's support of a colleague's temporary visa application or sponsorship of a colleague for permanent residence be construed to guarantee success of that application or amend or otherwise invalidate the "at-will" employment relationship between the colleague and Pfizer.
To apply, please click here
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